A vector-based method for drawing RNA secondary structure

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چکیده

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A vector-based method for drawing RNA secondary structure

MOTIVATION To produce a polygonal display of RNA secondary structure with minimal overlap and distortion of structural elements, with minimal search for positioning them, and with minimal user intervention. RESULTS A new algorithm for automatically drawing RNA secondary structure has been developed. The algorithm represents the direction and space for a structural element using vector and vec...

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Efficient drawing of RNA secondary structure

In this paper, we propose a new layout algorithm that draws the secondary structure of a Ribonucleic Acid (RNA) automatically according to some of the biologists’ aesthetic criteria. Such layout insures that two equivalent structures (or sub-structures) are drawn in a same and planar way. In order to allow a visual comparison of two RNAs, we use an heuristic that places the biggest similar part...

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New Method for Predicting RNA Secondary Structure

It has become clear recently that there are many RNAs that are not translated into proteins, instead they work as functional molecules. These RNAs are called “non-coding RNAs.” Predicting the secondary structure of these RNAs is important for understanding their functions. We will therefore focus on Nussinov’s algorithm and the SCFG version of Nussinov’s algorithm as useful techniques for predi...

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Method for predicting RNA secondary structure.

We report a method for predicting the most stable secondary structure of RNA from its primary sequence of nucleotides. The technique consists of a series of three computer programs interfaced to take the nucleotide sequence of any RNA and (a) list all possible helical regions, using modified Watson-Crick base-pairing rules; (b) create all possible secondary structures by forming permutations of...

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VARNA: Interactive drawing and editing of the RNA secondary structure

DESCRIPTION VARNA is a tool for the automated drawing, visualization and annotation of the secondary structure of RNA, designed as a companion software for web servers and databases. FEATURES VARNA implements four drawing algorithms, supports input/output using the classic formats dbn, ct, bpseq and RNAML and exports the drawing as five picture formats, either pixel-based (JPEG, PNG) or vecto...

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ژورنال

عنوان ژورنال: Bioinformatics

سال: 1999

ISSN: 1367-4803,1460-2059

DOI: 10.1093/bioinformatics/15.4.286